What Is Preimplantation Genetic Diagnosis (PGD)?

PGD is used to diagnose embryos for known genetic disorders in both partners such as:

  • Beta Thalessemia Trait
  • Sickle Cell
  • Cystic Fibrosis
  • SMA 1
  • Tay Sachs
  • Fragile X
  • Downs Syndrome

What Is Preimplantation Genetic Screening (PGS)?

Preimplantation genetic screening (PGS) screens embryos to ensure 23 pairs of chromosomes (22 autosomes and the sex chromosomes X & Y) are present and there is no aneuploidy. PGS is done in:

  • Women of advanced maternal age
  • Couples with history multiple miscarriages
  • Couples with previous IVF failure
  • Male factor infertility

How is PGS/PGD performed?

  • The PGS treatment involves the basic steps of IVF
  • Hormonal injections to grow multiple eggs in the ovaries
  • Removing the eggs through trans vaginal aspiration
  • Fertilization of eggs with sperms in IVF laboratory
  • Biopsy of embryos on day 3 or day 5 (preferable)
  • In day 3 embryo, blastomere is extracted from the 6-8 cell embryos and sent for the PGS/PGD in the genetic lab. If the results are good, healthy embryos can be transferred in the uterus on day 5.
  • In day 5 blastocyst, the biopsy of the trophectoderm is sent for the PGS/PGD. If the results are good, the embryos are frozen for the next cycle.

What are the risks involved with PGS/PGD?

  • PGD and PGS requirein vitro fertilization (IVF), which in itself is associated with certain risks such as ovarian hyper stimulation syndrome, multiple pregnancy, and increased risk of birth defects.
  • Biopsy or freezing that is done during the process may harm the embryo(s).
  • False negative results can occur i.e. genetic abnormalities are there in the embryo but cannot be detected during the testing. This can lead to the transfer of abnormal embryo in the uterus causing miscarriage. Also, healthy embryos are discarded, reducing the chances of a healthy pregnancy.
  • There is no guarantee of a healthy baby since this test does not screen for all possible genetic diseases or disorders.

What are the benefits of PGS/PGD?

  • PGD and PGS can help detect known genetic diseases or chromosomal abnormalities in the embryo. This can prevent unhealthy embryos from being transferred to uterus.
  • Decreases risk to couples or individuals with serious inherited disorders of having children affected with same problem.

Together, our team is committed towards prioritizing our patients while providing honest, ethical, compassionate, and affordable treatment. It is our promise that just when you feel you ought to ‘Give up’, we will stand by you and tell you ‘Try one more time’.

Our first consultation with Mr. Bachan Singh was an eye-opener. He patiently listened to our concerns, fears, and expectations, giving us personalized attention and care. The doctor took the time to explain the entire IVF process in detail, outlining the various treatment options tailored to our specific needs. We felt empowered and well-informed, knowing that the decisions made were based on thorough assessments and expertise. Thank You so much Joyce and the Team.
Krishan Dhankhar
1st time success,we are happy. Success rate is awesome Staff is very hardworking Tnks u joyce IVF team
Farhan Anwar
Superb and mind blowing setup of everything there even All Doctors and other medical staff everyone is supportive 🙌so you guys can visit freely if you want a genuine Treatment of IVF ✅❤️
Shama Parveen
The facility itself is also top-notch. It's clean, modern, and equipped with the latest technology and equipment. We always felt comfortable and at ease during our visits, which is so important when undergoing such a stressful and emotional process thanku JOyce IVF
Ismail Raja
Overall, I cannot recommend the Joyce IVF Centre highly enough. If you're struggling with infertility and looking for a compassionate and effective fertility clinic, look no further than the Joyce IVF Centre. They truly are the best of the best.

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